Selected publications:

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- Miragaia, R.J., Gomes, T., Chomka, A., Jardine, L., Riedel, A., Hegazy, A.N., Whibley, N., Tucci, A., Chen, X., Lindeman, I., Emerton, G., Krausgruber, T., Shields, J., Haniffa, M., Powrie, F., Teichmann, S.A., 2019. Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation. Immunity 50, 493–504.e7.
- Stockenhuber, K., Hegazy, A.N., West, N.R., Ilott, N.E., Stockenhuber, A., Bullers, S.J., Thornton, E.E., Arnold, I.C., Tucci, A., Waldmann, H., Ogg, G.S., Powrie, F., 2018. Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I-driven CD8+ T cell response. Journal of Experimental Medicine 215, 1987–1998.
- West, N.R., Owens, B.M.J., Hegazy, A.N., 2018. The oncostatin M-stromal cell axis in health and disease. Scand J Immunol 176, e12694.
- Hegazy* A.N., West* N.R., Stubbington, M.J.T., Wendt E.,  Suijker, K., Datsi, A., This, S., Danne, C., Campion, S., Duncan, S.H., Owens, B.M.J., Uhlig, H.H., McMichael, A., Oxford IBD Cohort Investigators, Bergthaler, A., Teichmann, S.A., Keshav, S., Powrie, F., 2017. Gut Microbiota Induce Local And Systemic CD4 T Cell Responses In Healthy Individuals That Are Altered In Inflammatory Bowel Diseases. Gastroenterology 153(5):1320-1337 (IF 16.8, cited 5)
- West* N.R., Hegazy* A.N., Owens B.M.J., Görtz D., This S., Ryzhakov G., Bullers S., Rahman N., Owens R., Müller-Newen G., Powrie F., 2017. Oncostatin M drives intestinal inflammation in mice and its abundance predicts response to tumor necrosis factor-neutralizing therapy in  patients with inflammatory bowel disease. Nat Med 23(5):579-589 (IF 32.6, cited 17)
- Bhattacharya*, A., Hegazy*, A.N., Deigendesch, N., Kosack, L., Cupovic, J., Kandasamy, R.K., Hildebrandt, A., Merkler, D., Kühl, A.A., Vilagos, B., Schliehe, C., Panse, I., Khamina, K., Baazim, H., Arnold, I., Flatz, L., Xu, H.C., Lang, P.A., Aderem, A., Takaoka, A., Superti-Furga, G., Colinge, J., Ludewig, B., Löhning, M., Bergthaler, A., 2015. Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity 43, 974–986. (IF 22.9, cited 17)
- Hegazy, A.N., Powrie, F., 2015. Microbiota RORgulates intestinal suppressor T cells. Science 349, 929–930. (IF 38, cited 13)
- Arnold, I.C., Mathisen, S., Schulthess, J., Danne, C., Hegazy, A.N., Powrie, F., 2016. CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23. Mucosal immunology 9, 352–363. (IF: 7.2, cited 23)
- Schiering, C., Krausgruber, T., Chomka, A., Fröhlich, A., Adelmann, K., Wohlfert, E.A., Pott, J., Griseri, T., Bollrath, J., Hegazy, A.N., Harrison, O.J., Owens, B.M.J., Löhning, M., Belkaid, Y., Fallon, P.G., Powrie, F., 2014. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature 513, 564–568. (IF 41.4, cited 260)
- Peine, M., Rausch, S., Helmstetter, C., Fröhlich, A., Hegazy, A.N., Kühl, A.A., Grevelding, C.G., Höfer, T., Hartmann, S., Löhning, M., 2013. Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. PLoS Biol. 11, e1001633. (IF 10.7, cited 50)
- Bonilla, W.V., Fröhlich, A., Senn, K., Kallert, S., Fernandez, M., Johnson, S., Kreutzfeldt, M., Hegazy, A.N., Schrick, C., Fallon, P.G., Klemenz, R., Nakae, S., Adler, H., Merkler, D., Löhning, M., Pinschewer, D.D., 2012. The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses. Science 335, 984–989. (IF 34.9, cited 164)
- Bergthaler, A., Flatz, L., Hegazy, A.N., Johnson, S., Horvath, E., Löhning, M., Pinschewer, D.D., 2010. Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression. Proceedings of the National Academy of Sciences 107, 21641–21646. (IF 10.2, cited 43)
- Flatz, L., Hegazy*, A.N., Bergthaler*, A., Verschoor*, A., Claus, C., Fernandez, M., Gattinoni, L., Johnson, S., Kreppel, F., Kochanek, S., Broek, M.V.D., Radbruch, A., Lévy, F., Lambert, P.-H., Siegrist, C.-A., Restifo, N.P., Löhning, M., Ochsenbein, A.F., Nabel, G.J., Pinschewer, D.D., 2010. Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nat Med 16, 339–345. (IF 32.6, cited 69)
- Hegazy, A.N., Peine, M., Helmstetter, C., Panse, I., Fröhlich, A., Bergthaler, A., Flatz, L., Pinschewer, D.D., Radbruch, A., Löhning, M., 2010. Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions. Immunity 32, 116–128. (IF 22.9, cited 179)
- Tokoyoda, K., Zehentmeier, S., Hegazy, A.N., Albrecht, I., Grün, J.R., Löhning, M., Radbruch, A., 2009. Professional Memory CD4+ T Lymphocytes Preferentially Reside and Rest in the Bone Marrow. Immunity 30, 721–730. (IF 22, cited 190)
- Hegazy, A.N., Klein, C., 2008. Ex vivo priming of CD4 T cells converts immunological tolerance into effective antitumor immunity in a murine model of acute lymphoblastic leukemia. Leukemia 22, 2070–2079. (IF 9.8, cited 6)
- Löhning, M., Hegazy, A.N., Pinschewer, D.D., Busse, D., Lang, K.S., Höfer, T., Radbruch, A., Zinkernagel, R.M., Hengartner, H., 2008. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. J Exp Med 205, 53–61. (IF 13, cited 84)
- Lang, K.S., Hegazy, A.N., Lang, P.A., Eschli, B., Löhning, M., Hengartner, H., Zinkernagel, R.M., Recher, M., 2007. “Negative vaccination” by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses. PLoS ONE 2, e1162. (IF 3.3, cited 11)
- Rudolph, C., Hegazy, A.N., Neuhoff, von, N., Steinemann, D., Schröck, E., Stripecke, R., Klein, C., Schlegelberger, B., 2005. Cytogenetic characterization of a BCR-ABL transduced mouse cell line. Cancer Genet. Cytogenet. 161, 51–56. (IF 1.5, cited